The CRI™ Algorithm

The Compensatory Reserve Index (CRI™) algorithm is the first application to emerge from the CipherSensor™ platform.  The CRI algorithm trends a patient’s intravascular volume, relative to the individual patient’s response to hypovolemia. Flashback's CRI monitors estimate compensatory reserve values based on non-invasive arterial waveforms such as the photoplethysmogram (PPG) signal used by pulse-oximeters. The CRI algorithm continuously analyzes and compares the entirety of each PPG waveform in a window of time to trend waveform features that are indicative of intravascular volume loss. Early identification of aberrant physiology would allow healthcare providers to intervene when the physiology is less complex and more likely to respond to therapy.  Our algorithms are designed to assist clinicians in quickly identifying and appropriately managing the most severely ill and injured patients.

Flashback has received U.S. FDA clearance to market the first device containing the Compensatory Reserve Index (CRI™) algorithm. Flashback’s commercial launch of its first CRI product is expected in 2017.