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Flashback CRI™ 

The Compensatory Reserve Index (CRI™) is a proprietary technology of Flashback Technologies Inc. (Louisville, CO). CRI is the first application to emerge from Flashback's  CipherSensor™ data analytics platform.  CRI trends a patient’s intravascular volume, relative to the individual patient’s response to hypovolemia. 

  • Standard vital signs do not deteriorate with hemorrhage until the patient is near collapse, due to a variety of compensatory mechanisms
  • The Compensatory Reserve Index (CRI™) is a new, simple to use, real-time parameter that provides a unique window into human hemodynamics
  • CRI measures an individual’s ability to compensate for additional intravascular volume loss, from normovolemia to hypovolemia to cardiovascular (CV)  collapse 
      • Enables early detection and monitoring of hemorrhage on a single scale (1-0) for all patients
      • The CRI Fuel gauge
  • CRI can be calculated from simple, well established sensor technologies that capture the pulsatile component of the cardiac cycle
  • CRI is the first in a new class of CV status indicators cleared by the FDA

To date Flashback’s CRI monitor has been validated a range of clinical studies in simulated hemorrhage (lower body negative pressure (LBNP)), low (<500ml) and moderate (~20% total blood volume) controlled blood draws and several clinical studies in trauma. 

Flashback has received U.S. FDA clearance to market the first device containing the Compensatory Reserve Index (CRI™) algorithm. Flashback’s commercial launch of its first CRI product, the CipherOx CRI™ M1, is pending.

CipherOX CRI M1